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The Piscassic River is a 15.3 mile long (24.6 km) river located in southeastern New Hampshire in the United States. It is a tributary of the Lamprey River, part of the Great Bay and Piscataqua River watershed leading to the Atlantic Ocean. The river rises in the northeast corner of Fremont, New Hampshire and flows east across flat, swampy terrain through the town of Epping. Upon reaching the town of Newfields, where it is joined by the Fresh River, the river turns northeast and winds through rolling terrain to Newmarket, where it reaches the Lamprey River. The Fresh River joins the Piscassic just upstream from the Piscassic Ice Pond in a marshy area of beaver ponds.